Rituxan And
RA
Rituxan and RA (rheumatoid
arthritis) is helping some of the 2 million adults in the
United States that are affected with this disease.
Rheumatoid arthritis is a progressive
autoimmune disease that involves inflammation of the joints and
surrounding tissue.
Over time rheumatoid arthritis can destroy
joints, ligaments, tendons and bone.
There have been several different
treatments used over the years to help treat the symptoms of
rheumatoid arthritis.
However, now a drug that is used to treat
cancer, Rituxan, has been approved by the Food and Drug
administration to be used in combination with Methotrexate to treat
rheumatoid arthritis.
Methotrexate is an antimetabolite. It
interferes with the way cells utilize essential nutrients. Because
of this, Methotrexate inhibits the activities of the immune system
reducing inflammation.
Rituxan targets a specific B immune cell
which are believed to play a role in the inflammation of rheumatoid
arthritis. Given together, they can greatly reduce the inflammation
in the joints.
Rituxan and rheumatoid arthritis helps by
reducing the signs and symptoms of the disease in adults who have
moderately to severe rheumatoid arthritis.
In order for a patient to be prescribed
Rituxan treatment they must have failed one or more of the
available drugs currently used to treat rheumatoid
arthritis.
Rituxan is given to patients as two 1000mg
IV infusion separated by two weeks and is generally given in an
outpatient infusion center. Along with all medications, Rituxan has
several side effects.
The side effects of Rituxan include nausea
or vomiting, weakness, headache, flushing or dizziness.
More serious side effects include
difficulty breathing, chest pain, irregular heart beat and no urine
production.
If you experience any of these side
effects call your doctor immediately.
The cost of treating rheumatoid arthritis
with Rituxan is very expensive.
This treatment method can range from
$16,000 to $20,000 a year. However, it holds a promise of eliciting
better outcomes than traditional rheumatoid arthritis treatments
with fewer side effects.
Rituxan and rheumatoid
arthritis so far is a winning combination. Patients are
having better results with Rituxan than what they had prior to
Rituxan becoming available. If other biologic treatments have
failed for you in the past, talk with your doctor and see if
Rituxan is right for you.
See
Also: Rheumatoid Arthritis
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